Alpha3beta1: A Potential Drug Target for Various Diseases (P34553)
Alpha3beta1: A Potential Drug Target for Various Diseases
The Integrin alpha3beta1 receptor (alpha3beta1) is a protein that is expressed in various tissues throughout the body, including the skin, hair, and nails. It plays a crucial role in cell-cell and cell-tissue interactions and is involved in many physiological processes, including cell migration, invasion, and adhesion.
Recent studies have identified alpha3beta1 as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The potential of alpha3beta1 as a drug target is based on its involvement in multiple signaling pathways and its expressed expression in a variety of tissues, including the brain, which suggests that it may be involved in the development and progression of these diseases.
One of the key mechanisms by which alpha3beta1 is involved in disease is its role in cell adhesion and migration. Alpha3beta1 is a critical regulator of cell-cell adhesion, allowing cells to stick together and form tissues. In addition, it is involved in the regulation of cell migration, which is essential for the development of tissues and organs during development and tissue repair.
Alpha3beta1 has also been shown to be involved in the regulation of inflammation and immune cell function. Its expression has been observed in a variety of immune cells, including T cells, NK cells, and macrophages, and its involvement in these processes suggests that it may play a role in the regulation of immune responses.
In addition to its role in cell-cell and cell-tissue interactions, alpha3beta1 is also involved in the regulation of gene expression. Its expression has been shown to be regulated by a variety of factors, including cytokines, growth factors, and DNA replication.
The potential of alpha3beta1 as a drug target is based on its involvement in multiple signaling pathways and its expressed expression in a variety of tissues. Its expression has also been implicated in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of alpha3beta1 in these diseases and to develop effective treatments.
Protein Name: Integrin Alpha3beta1 Receptor
More Common Targets
Integrin alpha4beta1 (VLA-4) receptor | Integrin alpha4beta7 (LPAM-1) receptor | Integrin alpha5beta1 (VLA-5) receptor | Integrin alpha5beta3 receptor | Integrin alpha6beta1 Receptor | Integrin alpha6beta4 receptor | Integrin alpha7beta1 Receptor | Integrin alpha9beta1 receptor | Integrin alphaEbeta7 receptor | Integrin alphaLbeta2 (LFA-1) receptor | Integrin alphaMbeta2 (MAC-1) Receptor | Integrin alphavbeta1 | Integrin alphavbeta3 (vitronectin) receptor | Integrin alphavbeta5 receptor | Integrin alphavbeta6 receptor | Integrin alphavbeta8 Receptor | Integrin Receptor | Integrin-linked kinase | Interferon | Interferon-alpha (IFN-alpha) | Interferon-gamma Receptor | Interleukin 17 | Interleukin 21 receptor complex | Interleukin 23 complex (IL-23) | Interleukin 35 | Interleukin-1 | Interleukin-1 receptor-associated kinase (IRAK) | Interleukin-12 (IL-12) | Interleukin-18 Receptor Complex | Interleukin-27 (IL-27) Complex | Interleukin-39 (IL-39) | Interleukin-7 receptor | Intraflagellar transport complex | Intraflagellar transport complex A | Intraflagellar transport complex B | Intrinsic Tenase Complex | INTS1 | INTS10 | INTS11 | INTS12 | INTS13 | INTS14 | INTS15 | INTS2 | INTS3 | INTS4 | INTS4P1 | INTS4P2 | INTS5 | INTS6 | INTS6L | INTS6L-AS1 | INTS6P1 | INTS7 | INTS8 | INTS9 | INTU | Invariant T Cell Receptor | INVS | Inward Rectifier Potassium Channel | IP6K1 | IP6K2 | IP6K3 | IPCEF1 | IPMK | IPO11 | IPO11-LRRC70 | IPO13 | IPO4 | IPO5 | IPO7 | IPO8 | IPO9 | IPO9-AS1 | IPP | IPPK | IPW | IQCA1 | IQCA1L | IQCB1 | IQCC | IQCD | IQCE | IQCF1 | IQCF2 | IQCF3 | IQCF5-AS1 | IQCF6 | IQCG | IQCH | IQCH-AS1 | IQCJ | IQCJ-SCHIP1 | IQCK | IQCM | IQCN | IQGAP1 | IQGAP2 | IQGAP3 | IQSEC1